4 the role of nutrition and obesity in epigenetics of type 2 diabetes
Epigenetic regulation of normal and malignant hematopoiesis
... CREB-binding protein Mol Cell Biol 21 : 22 49 22 58 Ernst P, Wang J, Korsmeyer SJ (20 02) The role of MLL in hematopoiesis and leukemia Curr Opin Hematol 9: 28 2 28 7 Esteller M (20 03) Profiling aberrant DNA ... complexes 2, and (PRC2/3/4) to RARb2 and NFE -2 target promoters (Villa et al., 20 06) PML-RARa co-purified with several components of the PRC multiprotein complex including SUZ 12 and EZH2, a HMTase ... Nature 4 42: 20 3 20 7 Ayton PM, Cleary ML (20 03) Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9 Genes Dev 17: 22 98 23 07 Balint BL, Gabor P, Nagy L (20 05a)...
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Báo cáo y học: "Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation" pps
... 12 13 14 15 16 17 18 19 20 21 22 23 24 Yudt MR, Cidlowski JA: The glucocorticoid receptor: coding a diversity of proteins and responses through a single gene Mol Endocrinol 20 02, 16:1719-1 726 ... stromal cell-derived factor (CXCL 12) , which supports distinct patterns and rates of CD4+ and CD8+ T cell migration within synovial tissue Arthritis Rheum 20 03, 48 :24 72- 24 82 Buckley CD, Filer A, Haworth ... transcription of 11beta-hydroxysteroid dehydrogenase type A novel mechanism for cross-talk between the C/EBP and glucocorticoid signaling pathways J Biol Chem 20 00, 27 5:3 023 2-3 023 9 Smith RE,...
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báo cáo khoa học: "CD7 in acute myeloid leukemia: correlation with loss of wild-type CEBPA, consequence of epigenetic regulation" potx
... qRT-PCR: +: 2^ -ΔΔct ≥ 5.0; (+) 2^ -ΔΔct ≥ 0 .2, < 5.0; -: 2^ -ΔΔct < 0 .2 The CEBPA-low cell line SET -2 was used as calibrator cell line CD7 qRT-PCR: +: 2^ ΔΔct > 2. 5; (+) 2^ -ΔΔct ≥ 1; -: 2^ -ΔΔct < ... 20 09, 2: 3 18 Scherr M, Battmer K, Ganser A, Eder M: Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA Cell Cycle 20 03, 2( 3) :25 1 -25 7 doi: 10.1186/1756-8 722 -3-15 ... C/EBPa in granulopoiesis Mol Cell Biol 20 01, 21 :3789-3806 12 Gardiner-Garden M, Frommer M: CpG islands in vertebrate genomes J Mol Biol 1987, 1 62: 261 -28 2 13 Weber M, Hellmann I, Stadler MB, Ramos...
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11 cb Exercises of Unit 12- 1
... hills and streams 31 Newcastle is _ a a city near the North East of England b a small town in England c a city in the North East of England d a city in the North of England 32 The population of ... passage and choose the best answer: I was born in Newcastle, a city in the North East of England Newcastle is on the bank of the River Tyne It is quite big, with a population of about 20 0,000 ... d over 22 Our sources of energy will soon end other sources are found a if b because c unless d otherwise 23 It’s very kind you to help me the money a to / with b of / with c of / about...
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11 cb Exercises of Unit 12- 2
... such as oil, coal and natural gas, provided over 82 percent of the commercial and industrial energy (2) ………… in the world Small amounts of energy were (3)…………… from nuclear fission, and the (4)……………… ... d It was Abraham Lincoln 2. Four miles off the southeastern coast of Massachusetts ………………., a popular summer resort a lies the island of Martha’s Vineyard b the island of Martha’s Vineyard lies ... Vineyard lies there c does lie the island of Martha’s Vineyard d where the island of Martha’s Vineyard lies Match each of the following names of sports and games with the appropriate sports report...
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Regulation of S Phase
... MCM4, -6, and -7 protein complex J Biol Chem 27 2 :24 508 24 513 Izumi M, Yatagai F, Hanaoka F (20 01) Cell cycle-dependent proteolysis and phosphorylation of human Mcm10 J Biol Chem 27 6:48 526 –48531 ... of HsORC4, a member of the human origin of replication recognition complex J Biol Chem 27 2 :28 247 28 251 Quintana DG, Thome KC, Hou ZH, Ligon AH, Morton CC, Dutta A (1998) ORC5L, a new member of ... S, Biamonti G (20 04) Modular structure of the human lamin B2 replicator Mol Cell Biol 24 :29 58 29 67 Parrilla-Castellar ER, Karnitz LM (20 03) Cut5 is required for the binding of Atr and DNA polymerase...
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Regulation of navigation and vessel-source pollution in the Northern Sea Route - Article 234 and state practice
... Martinus Nijhoff, 1993), pp 22 6, 23 2, 376–7 and 4 62; and M H Nordquist (editor-in-chief) with S Rosenne and S N Nandan (eds.), United Nations Convention on the Law of the Sea 19 82, A Commentary, Vol ... by the Norwegian, Russian and US ministries of defence, including the 1996 Declaration on Arctic Military Environmental Cooperation (AMEC). 127 120 121 122 123 124 125 127 V I Aleksin, ‘We Are Ready ... 15 of the Economic Zone Edict; Arts and 15 of the Environmental Edict; and Art 11 of the Decree of the Council of Ministers of the USSR, June 1990, ‘On Measures of Securing the Implementation of...
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Chapter 11 the cost of capital
... Goals: • Understand the cost of capital and the specific sources of capital associated with the cost of capital • Determine the cost of debt and preference share capital • Calculate cost of ordinary ... banker are 2% of the face value of the bond Calculation Method: Financial Calculator: n = 20 , PV = 960, PMT = -90, FV = 1,000 i = 9.5 42 Copyright © 20 11 Pearson Australia (a division of Pearson ... is $1 .2 million, the cost of preference share capital is: rp = $1 ,20 0,000 $10,000,000 rp = 12% Copyright © 20 11 Pearson Australia (a division of Pearson Australia Group Pty Ltd) – 97814 425 18193/...
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Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx
... Malhotra A, Vatner D & Abdellatif M (20 08) MicroRNA -21 targets Sprouty2 1616 18 19 20 21 22 23 24 25 26 27 28 and promotes cellular outgrowths Mol Biol Cell 19, 327 2– 328 2 Huang TH, Wu F, Loeb GB, Hsu ... of miR -22 1 and miR -22 2 in PC 12 cells, and that this induction is dependent on sustained activation of the ERK1 ⁄ pathway [20 ] Furthermore, the induction of miR-34a depends on the activation of ... Tsujimoto G (20 09) Sustained activation of ERK1 ⁄ by NGF induces microRNA -22 1 and 22 2 in PC 12 cells FEBS J 27 6, 326 9– 327 6 Ichimura A, Ruike Y, Terasawa K, Shimizu K & Tsujimoto G (20 10) MicroRNA-34a...
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Tài liệu Báo cáo khoa học: Regulation of DNA fragmentation: the role of caspases and phosphorylation doc
... Journal 27 8 (20 11) 427 –441 ª 20 10 The Authors Journal compilation ª 20 10 FEBS I Kitazumi and M Tsukahara 20 21 22 23 24 25 26 27 28 29 30 G on naked DNA and chromatin substrates J Biol Chem 27 6, ... and to apoptosis of human hepatoma HepG2 cells J Biol Chem 28 1, 21 256 21 265 Phosphorylation and caspases in DNA fragmentation 123 Geng Y, Walls KC, Ghosh AP, Akhtar RS, Klocke BJ & Roth KA (20 10) ... phosphatases types (PP1) and 2A (PP2A), is highly selective for PP2A FEBS Lett 416, 23 0 23 4 104 Boudreau RT, Conrad DM & Hoskin DW (20 07) Apoptosis induced by protein phosphatase 2A (PP2A) inhibition...
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Tài liệu Regulation of cancer cell metabolism docx
... p53 J Biol Chem 27 2, 22 776 22 780 (1997) 59 Bensaad, K et al TIGAR, a p53‑inducible regulator of glycolysis and apoptosis Cell 126 , 107– 120 (20 06) 60 Stambolic, V et al Regulation of PTEN transcription ... revIeWs | CanCer vOluMe 11 | FebruAry 20 11 | 93 © 20 11 Macmillan Publishers Limited All rights reserved REVIEWS 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 Stratton, M R., Campbell, P J & ... 4706–47 12 (1991) 70 Christofk, H R et al The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth Nature 4 52, 23 0 23 3 (20 08) The first mechanistic investigation of...
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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... 877–893 ª 20 09 The Authors Journal compilation ª 20 09 FEBS 889 CDE ⁄ CHR-dependent cell cycle-gene transcription 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 890 G A Muller and K Engeland ¨ transcription ... Gene 160, 27 7 28 1 Tavner F, Frampton J & Watson RJ (20 07) Targeting an E2F site in the mouse genome prevents promoter 25 26 27 28 29 30 31 32 33 34 35 36 37 38 silencing in quiescent and post-mitotic ... (1995) Identification of a cell -type- specific and E2F-independent mechanism for repression of cdc2 transcription Mol Cell Biol 15, 328 2– 329 0 Lam EW & Watson RJ (1993) An E2F-binding site mediates...
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Tài liệu Báo cáo khoa học: Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development doc
... Schorle H (20 05) The AP -2 family of transcription factors Genome Biol 6, 24 6, doi:10.1186/gb -20 05-6-13 -24 6 12 Moser M, Ruschoff J & Buettner R (1997) Comparative analysis of AP -2 alpha and AP -2 beta ... embryogenesis Especially for AP-2a, but also for AP-2b and AP-2e, a role as a regulator of cartilage differentiation has been shown [64–69] The functional and important roles of AP -2 transcription factors ... level of AP-2a expression that limits the size of the hand plate and the associated number of digit primordia [ 72] AP -2 function was also analyzed in other species A similar role for AP-2a as...
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Tài liệu Báo cáo khoa học: Regulation of the members of the mammalian heat shock factor family doc
... Heat shock factor (HSF2) contrib- Regulation of HSFs 17 18 19 20 21 22 23 24 25 26 27 28 29 utes to inducible expression of hsp genes through interplay with HSF1 J Biol Chem 28 2, 7077–7086 ˚ Akerfelt ... 137, 3177–3184 Mendell JT (20 08) miRiad roles for the miR-17- 92 cluster in development and disease Cell 133, 21 7 22 2 Kleene KC (20 03) Patterns, mechanisms, and functions of translation regulation ... factor isoforms in the rat seminiferous epithelium Exp Cell Res 24 0, 16 27 121 Schwob JE (20 02) Neural regeneration and the peripheral olfactory system Anat Rec 26 9, 33–49 122 Bhat SP (20 03) Crystallins,...
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Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt
... Marcusson EG, Ravichandran LV, Sun Y, Koo S, Perera RJ, Jain R 17 18 19 20 21 22 23 24 25 26 27 et al (20 04) MicroRNA-143 regulates adipocyte differentiation J Biol Chem 27 9, 523 61– 523 65 Wang Q, Li ... relevant role of miR -27 in the regulation of adipose tissue functions in vivo, we examined the expression of miR -27 in the genetically obese ob ⁄ ob mice The 23 52 expression levels of both miR -27 a and ... play a role in the regulation of miR -27 expression To test this hypothesis, we examined FEBS Journal 27 6 (20 09) 23 48 23 58 ª 20 09 The Authors Journal compilation ª 20 09 FEBS Q Lin et al miR -27 and...
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Tài liệu Báo cáo khoa học: Regulation of cathepsin B activity by 2A2 monoclonal antibody docx
... presence of various concentrations of 2A2 mAb The binding of 2A2 mAb was followed by native gel electrophoresis Increasing the concentration of 2A2 mAb at a fixed molar ratio of cathepsin B and cystatin ... and was found to be 2. 7 ± 1.8 nm, depicting a strong interaction between 2A2 mAb and cathepsin B Determination of the 2A2 mAb binding site on cathepsin B The binding site of 2A2 mAb on cathepsin ... epitope for 2A2 mAb, and the Kd for the interaction between 2A2 FEBS Journal 27 6 (20 09) 4739–4751 ª 20 09 The Authors Journal compilation ª 20 09 FEBS 4741 ´ B Mirkovic et al Regulation of cathepsin...
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Tài liệu Báo cáo khoa học: Mixed lineage leukemia histone methylases play critical roles in estrogen-mediated regulation of HOXC13 docx
... addition of E2 in ERE2 (Fig 5A, lanes and 4) These results demonstrated that ERE1 ( )23 4 bp) and ERE2 () 126 0 bp), FEBS Journal 27 6 (20 09) 7400–7411 ª 20 09 The Authors Journal compilation ª 20 09 FEBS ... and ERb to both ERE1 and ERE2 are different The binding of ERa is very low in the absence of E2, and is significantly enhanced in the presence of E2 n both ERE1 and ERE2 However, in the case of ... ERE1 and ERE2 (Fig 5B) In agreement with the above findings, binding of ERa and ERb was increased in both ERE1 and ERE2 in the presence of E2 Interestingly, the kinetics of E2-dependent binding of...
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Tài liệu Báo cáo khoa học: Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme ppt
... 50 2. 7 (2. 85 2. 7) 12. 3 (47 .2) 4.9 (1.3) 94 .2 (75.1) 10.0 (5.4) 111034 11131 120 20 11438 10539 9976 5 82 27 02 30 2. 6 (2. 67 2. 60) 24 .7 (30.1) 30.7 ( 32. 0) 29 0.016 563 27 06 30 2. 7 (2. 77 2. 70) 22 .8 ... Bfactor (A2) Bond length rms ˚ from ideal (A) Bond angle rmsd from ideal (deg) E138A:dTTP P6 322 1.046 50 2. 6 (2. 74 2. 6) 13.5 (51.5) 21 .9 (2. 6) 92. 7 (70.0) 12. 2 (5.5) 147198 120 85 H 121 A:dCTP P6 322 1.046 ... encoding the enzymes H 121 A and V 122 G were constructed to analyse the roles of His 121 and Val 122 in catalysis and regulation of dCTP deaminase Removal of the imidazole ring in H 121 A was anticipated...
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Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx
... Chem 27 9, 26 280 26 286 Dmitrieva NI & Burg MB (20 05) Hypertonic stress response Mutat Res 569, 65–74 Leong ML, Maiyar AC, Kim B, O’Keeffe BA & Firestone GL (20 03) Expression of the serum- and glucocorticoid-inducible ... Biophys 4 62, 189–194 28 Bortner CD & Cidlowski JA (20 07) Cell shrinkage and monovalent cation fluxes: role in apoptosis Arch Biochem Biophys 4 62, 176–188 29 Maeno E, Takahashi N & OkadaY (20 06) Dysfunction ... programs [25 ] Signaling mechanisms upstream of apoptotic volume decrease depend on the cell type and stimulus under investigation and have been discussed previously [26 – 28 ] The contribution of apoptotic...
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Tài liệu Báo cáo khoa học: Down-regulation of reduced folate carrier may result in folate malabsorption across intestinal brush border membrane during experimental alcoholism docx
... Journal 27 4 (20 07) 6317–6 328 ª 20 07 The Authors Journal compilation ª 20 07 FEBS A Hamid et al 10 11 12 13 14 15 16 17 18 19 20 21 apoptosis and cancer pathways in colon cancer cells Carcinogenesis 27 , ... patients: roles of alcohol and nutrition N Engl J Med 28 5, 701–706 Mason JB & Choi SW (20 05) Effects of alcohol on folate metabolism: implications for carcinogenesis Alcohol 35, 23 5 24 1 Purohit ... weight of ethanol FEBS Journal 27 4 (20 07) 6317–6 328 ª 20 07 The Authors Journal compilation ª 20 07 FEBS A Hamid et al (20 % solution) per day produced nontoxic blood alcohol concentrations, and rats...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25